15639968

Source:http://linkedlifedata.com/resource/pubmed/id/15639968

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007610, umls-concept:C0040649, umls-concept:C0040711, umls-concept:C0684063, umls-concept:C0725066, umls-concept:C1948027
pubmed:issue	6
pubmed:dateCreated	2005-1-10
pubmed:abstractText	It is well known that the processes of transcription and translation are coupled in prokaryotes. However, in eukaryotes, shortly after the transcription of the primary transcript begins, modifications and processing occur. After the mature mRNA moleculars are transported from the nuclei to the cytoplasm, the translations begin. It shows that the processes of transcription and translation are not coupled in eukaryotes. But now Iborra et al localized translation sites with [3H] lysine or lysyl-tRNA tagged with biotin or BODIPY in mammalian cells and found that there exited coupled transcription and translation within the nuclei. They estimated that the nuclear translation accounted for about 10% to 15% of protein synthesis in the cell.
pubmed:language	chi
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9436478
pubmed:status	PubMed-not-MEDLINE
pubmed:month	Nov
pubmed:issn	0253-9772
pubmed:author	pubmed-author:AnLi-JiaLJ, pubmed-author:GanQiangQ, pubmed-author:JinLi-JiLJ
pubmed:issnType	Print
pubmed:volume	25
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	718-20
pubmed:dateRevised	2006-11-15
pubmed:year	2003
pubmed:articleTitle	[The new advance of coupled transcription and translation: translation within the nuclei in eukaryotes].
pubmed:affiliation	Department of Bioscience and Biotechnology, Dalian University of Technology, Dalian 116024, China.
pubmed:publicationType	Journal Article, English Abstract