Linked Life Data

15639952

Source:http://linkedlifedata.com/resource/pubmed/id/15639952

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2005-1-10
pubmed:abstractText
This study is to explore the relationship between polymorphism of Catechol O-methyltransferase gene and schizophrenia. Search for a gene predisposing to schizophrenia in the Han nationality in China. Five pedigrees with high incidence of schizophrenia were studied by polymerize chain reaction(PCR) and restriction fragment length polymorphism(RFLP) technique. Statistics analysis of the transmission/disequilibrium test (TDT) showed that the COMT gene is associated with schizophrenia in the five pedigree with high incidence schizophrenia(P=0.0455). The results suggest that there might have a schizophrenia liability gene on 22 chromosome (22q11.2) in our studied pedigrees.
pubmed:language
chi
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Nov
pubmed:issn
0253-9772
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
652-4
pubmed:dateRevised
2006-11-15
pubmed:year
2003
pubmed:articleTitle
[Association study of five pedigree with high incidence of schizophrenia].
pubmed:affiliation
Department of Biological Psychiatry, Shenzhen Institute of Mental Health, Shenzhen 518020, China. wuhan9388@sina.com
pubmed:publicationType
Journal Article, English Abstract