Linked Life Data

15639943

Source:http://linkedlifedata.com/resource/pubmed/id/15639943

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2005-1-10
pubmed:abstractText
Microsatellites,simple sequence repeats (SSR),are abundant and distributed throughout the eukaryote genome. The contents of microsatellites are variant in different creatures. There are also different types of microsatellites, which are dominant in different creatures. One of the most noticeable characters of microsatellites is that they are easy to expand during DNA replication. It is thought to attribute to DNA slippage. This kind of mutation is affected by many factors. It is guessed that microsatellites come from pro-microsatellites, while the pro-microsatellites origin from random point mutations. The length of microsatellites can be maintained under relative conservative ranges during species evolution. As they are abundant, codominatnt,distributed over the euchromatic part of the genome, and have the character of highly polimorphic, microsatellites are useful tools for gene mapping, clinical diagnosis and predicting, paternity or pedigree analysis, evolution study, and marker-assisted breeding.
pubmed:language
chi
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Sep
pubmed:issn
0253-9772
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
615-9
pubmed:dateRevised
2006-11-15
pubmed:year
2003
pubmed:articleTitle
[The evolution and application of microsatellites].
pubmed:affiliation
The Key Laboratory of Gene Engineering of Ministry of Education, Zhongshan University, Guangzhou 510275, China. wenyongluo@yahoo.com
pubmed:publicationType
Journal Article, English Abstract