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pubmed-article:15638369pubmed:abstractTextThe aim of the study was to evaluate the correlation of c-erb-b2 and Bcl-xl expression in biopsy specimens of Barrett's oesophagus from 44 patients with morphological features. The examined group was subdivided into: negative for dysplasia, indefinite for dysplasia, positive for dysplasia-low grade, and adenocarcinoma with high grade dysplasia. Positive c-erb-B2 staining was found in 34.1% and Bcl-xl protein expression was observed in 96.9% of BE. The results showed increased c-erb-B2 and Bcl-xl protein expressions with progressive grades of dysplasia to adenocarcinoma. In conclusion, an evaluation of c-erb-B2 and Bcl-xl expression can be useful for the histopatologic diagnosis of BE and correct interpretation of dysplasia.lld:pubmed
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pubmed-article:15638369pubmed:volume49 Suppl 1lld:pubmed
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pubmed-article:15638369pubmed:dateRevised2009-11-19lld:pubmed
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pubmed-article:15638369pubmed:articleTitleC-erb-B2 and Bcl-xl protein expression in Barrett's oesophagus in correlation with morphological parameters.lld:pubmed
pubmed-article:15638369pubmed:affiliationDepartment of Pathology, Medical University of Bialystok, Poland.lld:pubmed
pubmed-article:15638369pubmed:publicationTypeJournal Articlelld:pubmed
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