Source:http://linkedlifedata.com/resource/pubmed/id/15635664
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2005-6-30
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pubmed:abstractText |
2-Oxoamides based on long chain beta-amino acids were synthesized. 1-Benzyl substituted long chain amines, needed for such synthesis, were synthesized starting from Boc-phenylalaninol. The oxidative conversion of a phenyl group to a carboxyl group was used as the key transformation synthetic step. The compounds synthesized were studied for their activity against GIVA PLA(2), and were proven to be weak inhibitors.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amino Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Formic Acid Esters,
http://linkedlifedata.com/resource/pubmed/chemical/Phenylalanine,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipases A,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/oxoamide,
http://linkedlifedata.com/resource/pubmed/chemical/phenylalaninol,
http://linkedlifedata.com/resource/pubmed/chemical/t-butyloxycarbonyl group
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1075-2617
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pubmed:author | |
pubmed:copyrightInfo |
Copyright (c) 2004 European Peptide Society and John Wiley & Sons, Ltd.
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pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
431-5
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading | |
pubmed:year |
2005
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pubmed:articleTitle |
Synthesis and activity of 2-oxoamides containing long chain beta-amino acids.
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pubmed:affiliation |
Chemical Laboratories, Agricultural University of Athens, Iera Odos 75, Athens 11855, Greece.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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