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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-2-1
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pubmed:abstractText |
The authors examined the impact of the number of CAG repeats in exon 1 of the androgen receptor on disease progression among men with prostate carcinoma after prostatectomy. This polymorphism has been associated with alterations in activity of the androgen receptor in in vitro systems and with the risk of clinically diagnosed prostate carcinoma in some epidemiologic studies. An earlier series found that, among men at low risk of progressive disease, a small number of CAG repeats predicted a high risk of recurrence, and the impact of CAG repeats varied among men with different risks of progressive disease.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
(c) 2004 American Cancer Society
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
528-37
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15630701-Adenine,
pubmed-meshheading:15630701-African Continental Ancestry Group,
pubmed-meshheading:15630701-Age Factors,
pubmed-meshheading:15630701-Aged,
pubmed-meshheading:15630701-Cytosine,
pubmed-meshheading:15630701-Disease Progression,
pubmed-meshheading:15630701-European Continental Ancestry Group,
pubmed-meshheading:15630701-Exons,
pubmed-meshheading:15630701-Genotype,
pubmed-meshheading:15630701-Guanine,
pubmed-meshheading:15630701-Humans,
pubmed-meshheading:15630701-Male,
pubmed-meshheading:15630701-Middle Aged,
pubmed-meshheading:15630701-Neoplasm Staging,
pubmed-meshheading:15630701-Odds Ratio,
pubmed-meshheading:15630701-Prostate-Specific Antigen,
pubmed-meshheading:15630701-Prostatectomy,
pubmed-meshheading:15630701-Prostatic Neoplasms,
pubmed-meshheading:15630701-Receptors, Androgen,
pubmed-meshheading:15630701-Survival Analysis,
pubmed-meshheading:15630701-Trinucleotide Repeats
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pubmed:year |
2005
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pubmed:articleTitle |
The impact of CAG repeats in exon 1 of the androgen receptor on disease progression after prostatectomy.
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pubmed:affiliation |
Barbara Ann Karmanos Cancer Institute and Department of Medicine, Wayne State University School of Medicine, Detroit, Michigan, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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