Linked Life Data

15627245

Source:http://linkedlifedata.com/resource/pubmed/id/15627245

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-3-28
pubmed:abstractText
Most biocements are two- or three-component acid-based systems with large differences in the component particle sizes, which occurs by virtue of the differing processing routes. This work aimed to improve injectability and strength of a single reactive component cement, that is, mechanically activated alpha-tricalcium phosphate (TCP)-based cement by adding 13-33 wt % of several fine-particle-sized (d(50) of 0.5-1.1 microm) fillers [dicalcium phosphate anhydrous (DCPA), titanium dioxide (TiO(2)), and calcium carbonate] to the monomodal alpha-TCP matrix (d(50) = 9.8 microm). A high zeta-potential was measured for all particles in trisodium citrate solution. The fraction of alpha-TCP cement "injected" through an 800-microm hypodermic needle was found to be only 35% at a powder-to-liquid ratio of 3.5 g/mL. In contrast, the use of fillers decreased cement viscosity to a point, where complete injectability could be obtained. Mechanistically, these additives disrupted alpha-TCP particle packing yet decreased the interparticle spacing by a factor of approximately 5.5 such that the electrostatic repulsion effect was enhanced. A strength improvement was found when DCPA and TiO(2) were used as fillers despite the lower degree of conversion of these cements. Compressive strengths of precompacted cement samples increased from 70 MPa for unfilled alpha-TCP cement to 140 (110) MPa for 23 wt % DCPA (or TiO(2)) fillers as a result of porosity reduction. Strength improvement for more clinically relevant uncompacted cements was achieved by higher powder-to-liquid ratio mixes for filled cements such that maximum strengths of 90 MPa were obtained for 23 wt % DCPA filler compared with 50 MPa for single-component alpha-TCP cement.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1552-4973
pubmed:author
pubmed:copyrightInfo
(c) 2004 Wiley Periodicals, Inc.
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-6
pubmed:dateRevised
2006-6-22
pubmed:meshHeading
pubmed-meshheading:15627245-Biocompatible Materials, pubmed-meshheading:15627245-Calcium Carbonate, pubmed-meshheading:15627245-Calcium Phosphates, pubmed-meshheading:15627245-Citrates, pubmed-meshheading:15627245-Compressive Strength, pubmed-meshheading:15627245-Dental Cements, pubmed-meshheading:15627245-Dental Cementum, pubmed-meshheading:15627245-Dose-Response Relationship, Drug, pubmed-meshheading:15627245-Hardness, pubmed-meshheading:15627245-Ions, pubmed-meshheading:15627245-Macromolecular Substances, pubmed-meshheading:15627245-Materials Testing, pubmed-meshheading:15627245-Models, Chemical, pubmed-meshheading:15627245-Porosity, pubmed-meshheading:15627245-Rheology, pubmed-meshheading:15627245-Surface Properties, pubmed-meshheading:15627245-Tensile Strength, pubmed-meshheading:15627245-Titanium, pubmed-meshheading:15627245-X-Ray Diffraction
pubmed:year
2005
pubmed:articleTitle
Rheological enhancement of mechanically activated alpha-tricalcium phosphate cements.
pubmed:affiliation
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, D-97070 Würzburg, Germany.
pubmed:publicationType
Journal Article