Source:http://linkedlifedata.com/resource/pubmed/id/15626899
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
2004-12-31
|
pubmed:abstractText |
Infliximab, an anti-tumor necrosis factor (TNF) monoclonal antibody, might exert some of its long-term therapeutic effects in Crohn's disease (CD) by interacting directly with cells of the immune system such as monocytes and T lymphocytes via membrane TNF and by inducing apoptosis. Accordingly, the effects of inflix-imab on monocyte apoptosis and down-regulation of proinflammatory cytokines (reverse signaling) were assessed.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1078-0998
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
801-10
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15626899-Antibodies, Monoclonal,
pubmed-meshheading:15626899-Apoptosis,
pubmed-meshheading:15626899-Case-Control Studies,
pubmed-meshheading:15626899-Crohn Disease,
pubmed-meshheading:15626899-Gastrointestinal Agents,
pubmed-meshheading:15626899-Humans,
pubmed-meshheading:15626899-Monocytes,
pubmed-meshheading:15626899-Tumor Necrosis Factor-alpha
|
pubmed:year |
2004
|
pubmed:articleTitle |
Effects of infliximab on apoptosis and reverse signaling of monocytes from healthy individuals and patients with Crohn's disease.
|
pubmed:affiliation |
North Shore-Long Island Jewish Health System, Schneider Children's Hospital, New Hyde Park, New York, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|