Linked Life Data

15623649

Source:http://linkedlifedata.com/resource/pubmed/id/15623649

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
24
pubmed:dateCreated
2004-12-29
pubmed:abstractText
Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, also called statins, are currently used widely as a safe, effective therapeutic in the treatment of hypercholesterolemia. Recently, statins have been recognized for their activity against cancer. In the present study, we examined the effect of a synthetic statin, fluvastatin, on the development of renal cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/CDKN1A protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cdkn1a protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Cell Cycle Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Cyclin-Dependent Kinase Inhibitor..., http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Monounsaturated, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl CoA Reductases, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA..., http://linkedlifedata.com/resource/pubmed/chemical/Indoles, http://linkedlifedata.com/resource/pubmed/chemical/Neuropeptides, http://linkedlifedata.com/resource/pubmed/chemical/Rac1 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53, http://linkedlifedata.com/resource/pubmed/chemical/fluvastatin, http://linkedlifedata.com/resource/pubmed/chemical/rac GTP-Binding Proteins
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
8648-55
pubmed:dateRevised
2005-11-17
pubmed:meshHeading
pubmed-meshheading:15623649-Animals, pubmed-meshheading:15623649-Antibiotic Prophylaxis, pubmed-meshheading:15623649-Apoptosis, pubmed-meshheading:15623649-Blotting, Western, pubmed-meshheading:15623649-Carcinoma, Renal Cell, pubmed-meshheading:15623649-Cell Cycle Proteins, pubmed-meshheading:15623649-Cell Proliferation, pubmed-meshheading:15623649-Cyclin-Dependent Kinase Inhibitor p21, pubmed-meshheading:15623649-Fatty Acids, Monounsaturated, pubmed-meshheading:15623649-G1 Phase, pubmed-meshheading:15623649-Humans, pubmed-meshheading:15623649-Hydroxymethylglutaryl CoA Reductases, pubmed-meshheading:15623649-Hydroxymethylglutaryl-CoA Reductase Inhibitors, pubmed-meshheading:15623649-Indoles, pubmed-meshheading:15623649-Kidney Neoplasms, pubmed-meshheading:15623649-Lung Neoplasms, pubmed-meshheading:15623649-Male, pubmed-meshheading:15623649-Mice, pubmed-meshheading:15623649-Mice, Inbred BALB C, pubmed-meshheading:15623649-Neoplasm Invasiveness, pubmed-meshheading:15623649-Neovascularization, Pathologic, pubmed-meshheading:15623649-Neuropeptides, pubmed-meshheading:15623649-Phosphorylation, pubmed-meshheading:15623649-Tumor Cells, Cultured, pubmed-meshheading:15623649-Tumor Suppressor Protein p53, pubmed-meshheading:15623649-rac GTP-Binding Proteins
pubmed:year
2004
pubmed:articleTitle
3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis.
pubmed:affiliation
Department of Urology, National Defense Medical College, Saitama, Japan. impreza@cb3.so-net.ne.jp
pubmed:publicationType
Journal Article