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rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007137,
umls-concept:C0007600,
umls-concept:C0008838,
umls-concept:C0017262,
umls-concept:C0030705,
umls-concept:C0036667,
umls-concept:C0185117,
umls-concept:C0312418,
umls-concept:C0314603,
umls-concept:C0460004,
umls-concept:C0683598,
umls-concept:C1979963,
umls-concept:C2003903,
umls-concept:C2911684
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|
pubmed:issue |
24
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|
pubmed:dateCreated |
2004-12-29
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|
pubmed:abstractText |
The choice of treatment for squamous cell carcinoma of the head and neck (SCCHN) is still primarily based on the tumor-node-metastasis classification. However, it is reasonable to believe that biological profiles of SCCHN may be independently associated with response to therapy. The aim of the present study was to examine genetic changes and gene expression profiles that might correlate with sensitivity to cisplatin [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay] in 10 SCCHN cell lines.
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pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
pubmed-author:AkervallJanJ,
pubmed-author:AndersonHaraldH,
pubmed-author:BradfordCarolC,
pubmed-author:CareyThomasT,
pubmed-author:ColeAndrewA,
pubmed-author:GuoXiangX,
pubmed-author:KortEricE,
pubmed-author:LeeserBrandonB,
pubmed-author:QianChao-NanCN,
pubmed-author:ResauJamesJ,
pubmed-author:SchoumansJacquelineJ,
pubmed-author:TehBin TBT,
pubmed-author:TennvallJanJ,
pubmed-author:WennerbergJohanJ
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|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
10
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
8204-13
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|
pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15623595-Adult,
pubmed-meshheading:15623595-Aged,
pubmed-meshheading:15623595-Aged, 80 and over,
pubmed-meshheading:15623595-Antineoplastic Agents,
pubmed-meshheading:15623595-Carcinoma, Squamous Cell,
pubmed-meshheading:15623595-Cisplatin,
pubmed-meshheading:15623595-Down-Regulation,
pubmed-meshheading:15623595-Drug Resistance, Neoplasm,
pubmed-meshheading:15623595-Female,
pubmed-meshheading:15623595-Gene Expression Profiling,
pubmed-meshheading:15623595-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15623595-Head and Neck Neoplasms,
pubmed-meshheading:15623595-Humans,
pubmed-meshheading:15623595-Male,
pubmed-meshheading:15623595-Middle Aged,
pubmed-meshheading:15623595-Nucleic Acid Hybridization,
pubmed-meshheading:15623595-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:15623595-Ploidies,
pubmed-meshheading:15623595-Proto-Oncogene Proteins c-met,
pubmed-meshheading:15623595-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:15623595-Spectral Karyotyping,
pubmed-meshheading:15623595-Tumor Cells, Cultured,
pubmed-meshheading:15623595-Tumor Markers, Biological
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|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Genetic and expression profiles of squamous cell carcinoma of the head and neck correlate with cisplatin sensitivity and resistance in cell lines and patients.
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|
pubmed:affiliation |
Department of Otolaryngology, Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA.
|
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
