Source:http://linkedlifedata.com/resource/pubmed/id/15622728
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2004-12-29
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pubmed:abstractText |
Mice of the O'Grady strain which were inbred for susceptibility to audiogenic seizures were found to be more sensitive to pentamethylenetetrazol (Metrazol) convulsions than mice of the parent Swiss-Webster strain from which they were originally derived. A dose of 35 mg/kg Metrazol was required to produce a 50% convulsive response (CD50) in O'Grady mice and 50 mg/kg in the control parent strain. No differences in convulsive thresholds to Metrazol were obtained, however, between untreated Swiss-Webster mice and mice of the same strain made audiosuseptible by rubidium chloride intake or magnesium deficiency.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0161-813X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
91-5
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pubmed:meshHeading |
pubmed-meshheading:15622728-Acoustic Stimulation,
pubmed-meshheading:15622728-Animals,
pubmed-meshheading:15622728-Convulsants,
pubmed-meshheading:15622728-Epilepsy, Reflex,
pubmed-meshheading:15622728-Magnesium Deficiency,
pubmed-meshheading:15622728-Male,
pubmed-meshheading:15622728-Mice,
pubmed-meshheading:15622728-Pentylenetetrazole,
pubmed-meshheading:15622728-Rubidium
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pubmed:year |
1981
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pubmed:articleTitle |
Metrazol thresholds in inbred and non-inbred audiosensitive mice.
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pubmed:affiliation |
New York State Psychiatric Institute, New York, NY 10032, USA.
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pubmed:publicationType |
Journal Article
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