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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2004-12-28
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pubmed:abstractText |
Active Crohn's disease (CD) is often associated with elevated levels of platelets, granulocytes, and monocytes that are activated and resistant to apoptosis. The level of neutrophils in the intestinal mucosa has been quantitatively related to the severity of intestinal inflammation in CD. We postulated that patients with CD that is refractory to conventional medications might respond to a reduction of granulocytes and monocytes by adsorptive apheresis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0944-1174
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pubmed:author |
pubmed-author:FukudaYoshihiroY,
pubmed-author:HibiToshifumiT,
pubmed-author:HonmaTerasuT,
pubmed-author:KankeKazunariK,
pubmed-author:MatsuiToshiyukiT,
pubmed-author:MatsumotoTakayukiT,
pubmed-author:MotoyaSatoshiS,
pubmed-author:SawadaKojiK,
pubmed-author:ShimoyamaTakashiT,
pubmed-author:SuzukiYasuoY,
pubmed-author:TakazoeMasakazuM,
pubmed-author:YaoTsuneyoshiT
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pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1158-64
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15622479-Adolescent,
pubmed-meshheading:15622479-Adult,
pubmed-meshheading:15622479-Blood Component Removal,
pubmed-meshheading:15622479-Child,
pubmed-meshheading:15622479-Crohn Disease,
pubmed-meshheading:15622479-Female,
pubmed-meshheading:15622479-Granulocytes,
pubmed-meshheading:15622479-Humans,
pubmed-meshheading:15622479-Male,
pubmed-meshheading:15622479-Middle Aged,
pubmed-meshheading:15622479-Monocytes,
pubmed-meshheading:15622479-Prospective Studies,
pubmed-meshheading:15622479-Treatment Outcome
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pubmed:year |
2004
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pubmed:articleTitle |
Adsorptive granulocyte and monocyte apheresis for refractory Crohn's disease: an open multicenter prospective study.
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pubmed:affiliation |
Department of Gastroenterology, Hyogo College of Medicine, 1-1 Mukogawa, Nishinomiya, 663-8501, Japan.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
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