Linked Life Data

15619665

Source:http://linkedlifedata.com/resource/pubmed/id/15619665

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-12-27
pubmed:abstractText
We examined the direct effect of SC-19220, an EP1 prostaglandin (PG) E2 receptor antagonist, on osteoclastogenesis induced by RANK/RANKL signaling in mouse cell cultures. We found that SC-19220 inhibited RANKL-induced osteoclastogenesis by suppression of the RANK/RANKL signaling pathway in osteoclast precursors.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/11-deoxyprostaglandin E1, http://linkedlifedata.com/resource/pubmed/chemical/Alprostadil, http://linkedlifedata.com/resource/pubmed/chemical/CSK tyrosine-protein kinase, http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins, http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Dibenz(b,f)(1,4)oxazepine-10(11H)-ca..., http://linkedlifedata.com/resource/pubmed/chemical/Dinoprostone, http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins, http://linkedlifedata.com/resource/pubmed/chemical/NFATC Transcription Factors, http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandin Antagonists, http://linkedlifedata.com/resource/pubmed/chemical/Protein-Tyrosine Kinases, http://linkedlifedata.com/resource/pubmed/chemical/Ptger1 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/RANK Ligand, http://linkedlifedata.com/resource/pubmed/chemical/Receptor Activator of Nuclear..., http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Prostaglandin E, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Prostaglandin E, EP1..., http://linkedlifedata.com/resource/pubmed/chemical/Tnfrsf11a protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Tnfsf11 protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0884-0431
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
15-22
pubmed:dateRevised
2011-11-2
pubmed:meshHeading
pubmed-meshheading:15619665-Alprostadil, pubmed-meshheading:15619665-Animals, pubmed-meshheading:15619665-Bone Marrow Cells, pubmed-meshheading:15619665-Carrier Proteins, pubmed-meshheading:15619665-DNA-Binding Proteins, pubmed-meshheading:15619665-Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid..., pubmed-meshheading:15619665-Dinoprostone, pubmed-meshheading:15619665-Down-Regulation, pubmed-meshheading:15619665-Female, pubmed-meshheading:15619665-Membrane Glycoproteins, pubmed-meshheading:15619665-Mice, pubmed-meshheading:15619665-Mice, Inbred Strains, pubmed-meshheading:15619665-NFATC Transcription Factors, pubmed-meshheading:15619665-Nuclear Proteins, pubmed-meshheading:15619665-Osteoclasts, pubmed-meshheading:15619665-Prostaglandin Antagonists, pubmed-meshheading:15619665-Protein-Tyrosine Kinases, pubmed-meshheading:15619665-RANK Ligand, pubmed-meshheading:15619665-Receptor Activator of Nuclear Factor-kappa B, pubmed-meshheading:15619665-Receptors, Prostaglandin E, pubmed-meshheading:15619665-Receptors, Prostaglandin E, EP1 Subtype, pubmed-meshheading:15619665-Transcription Factors
pubmed:year
2005
pubmed:articleTitle
SC-19220, antagonist of prostaglandin E2 receptor EP1, inhibits osteoclastogenesis by RANKL.
pubmed:affiliation
Department of Oral Microbiology, Kyushu Dental College, Kitakyushu, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't