Linked Life Data

1561938

Source:http://linkedlifedata.com/resource/pubmed/id/1561938

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1992-5-11
pubmed:abstractText
The angio-architectural and histological changes of small cerebral blood vessels in experimental hydrocephalus were studied to assess the changes of the vascular bed in the cerebral mantle. Change of the microvasculature assessed from microcorrosion casts by scanning electron microscopy (SEM) and the histological changes shown by light and electron microscopy were compared before and after shunting for hydrocephalus. The changes of the rCBF were also evaluated by the hydrogen clearance method. In hydrocephalus, a reduction in the number and caliber of the capillaries was noted in both the white and gray matter in the SEM study, but the capillaries were preserved and changes were mild and nonspecific in the electron microscopic examination. Shunting resulted in the reversal of all these changes to normal along with recovery of the rCBF, which had decreased in hydrocephalus. These observations suggest that changes of the vascular bed participate in the alteration of cerebral mantle width in the hydrocephalic process, and that the changes of the microvasculature result not only from damage to the capillaries themselves but also from changes of the perivascular structures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0001-6268
pubmed:author
pubmed:issnType
Print
pubmed:volume
114
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
43-50
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Changes in the cerebral vascular bed in experimental hydrocephalus: an angio-architectural and histological study.
pubmed:affiliation
Department of Neurosurgery, Toyama Medical and Pharmaceutical University, Japan.
pubmed:publicationType
Journal Article