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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2004-12-24
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pubmed:abstractText |
Lamivudine is a potent inhibitor of hepatitis B virus (HBV) replication. As other available HBV therapies, its efficacy is hampered by relapse after discontinuation and by the risk of viral breakthrough. A recent study suggests that pre-emptive lamivudine therapy improves survival in HBV renal transplants, but few data are available regarding its long-term use in this population. The clinical features, course and viral mutations associated with the emergence of viral resistance in this population have not been well studied.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0954-691X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1367-73
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pubmed:dateRevised |
2009-10-16
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pubmed:meshHeading |
pubmed-meshheading:15618847-Adult,
pubmed-meshheading:15618847-Alanine Transaminase,
pubmed-meshheading:15618847-Amino Acid Sequence,
pubmed-meshheading:15618847-DNA, Viral,
pubmed-meshheading:15618847-Drug Resistance, Viral,
pubmed-meshheading:15618847-Female,
pubmed-meshheading:15618847-Genes, Viral,
pubmed-meshheading:15618847-Hepatitis B, Chronic,
pubmed-meshheading:15618847-Hepatitis B virus,
pubmed-meshheading:15618847-Humans,
pubmed-meshheading:15618847-Kidney Transplantation,
pubmed-meshheading:15618847-Lamivudine,
pubmed-meshheading:15618847-Long-Term Care,
pubmed-meshheading:15618847-Male,
pubmed-meshheading:15618847-Middle Aged,
pubmed-meshheading:15618847-Molecular Sequence Data,
pubmed-meshheading:15618847-Mutation,
pubmed-meshheading:15618847-Polymerase Chain Reaction,
pubmed-meshheading:15618847-Reverse Transcriptase Inhibitors
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pubmed:year |
2004
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pubmed:articleTitle |
Long-term therapy with lamivudine in renal transplant recipients with chronic hepatitis B.
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pubmed:affiliation |
Hepato-gastroenterology Unit, Hôpital Pitié-Salpêtrière, Paris, France. dthabut@libertysurf.fr
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pubmed:publicationType |
Journal Article
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