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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-12-21
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pubmed:abstractText |
Proteinuria is a significant problem in medicine today, although glomerular events underlying it are unknown. Products of cytochrome P450 (CYP450) pathway of arachidonic acid metabolism are increasingly recognized as playing major roles in renal function. We used in vitro albumin permeability (P(alb)) as a measure of injury and puromycin aminonucleoside (PAN) as an injurious agent to test the hypothesis that 20-hydroxyeicosatetraenoic acid (20-HETE) protects the glomerular filtration barrier from increased P(alb).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
152-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15610238-Alkane 1-Monooxygenase,
pubmed-meshheading:15610238-Animals,
pubmed-meshheading:15610238-Clofibrate,
pubmed-meshheading:15610238-Cytochrome P-450 Enzyme System,
pubmed-meshheading:15610238-Glomerular Filtration Rate,
pubmed-meshheading:15610238-Hydroxyeicosatetraenoic Acids,
pubmed-meshheading:15610238-Kidney Glomerulus,
pubmed-meshheading:15610238-Male,
pubmed-meshheading:15610238-Permeability,
pubmed-meshheading:15610238-Proteinuria,
pubmed-meshheading:15610238-Puromycin Aminonucleoside,
pubmed-meshheading:15610238-Rats,
pubmed-meshheading:15610238-Rats, Sprague-Dawley
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pubmed:year |
2005
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pubmed:articleTitle |
Protective effect of 20-hydroxyeicosatetraenoic acid (20-HETE) on glomerular protein permeability barrier.
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pubmed:affiliation |
Divison of Nephrology, Medical College of Wisconsin, Milwaukee, Wisconsin.
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pubmed:publicationType |
Journal Article,
In Vitro
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