rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
2004-12-21
|
pubmed:abstractText |
Immune cells express heparanase, an endoglycosidase, able to degrade heparan sulfate glycosaminoglycan (HSGAG) in the glomerular capillary wall (GCW) and potentially induce proteinuria. The aim of this study was to determine whether dysregulated heparanase expression is associated with the heavy proteinuria of childhood steroid-sensitive nephrotic syndrome (SSNS).
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0085-2538
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
67
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
122-9
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15610235-Adult,
pubmed-meshheading:15610235-Age Factors,
pubmed-meshheading:15610235-Case-Control Studies,
pubmed-meshheading:15610235-Child,
pubmed-meshheading:15610235-Enzyme Activation,
pubmed-meshheading:15610235-Female,
pubmed-meshheading:15610235-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:15610235-Glucuronidase,
pubmed-meshheading:15610235-Heparitin Sulfate,
pubmed-meshheading:15610235-Humans,
pubmed-meshheading:15610235-Male,
pubmed-meshheading:15610235-Middle Aged,
pubmed-meshheading:15610235-Nephrotic Syndrome,
pubmed-meshheading:15610235-Protein Processing, Post-Translational,
pubmed-meshheading:15610235-RNA, Messenger,
pubmed-meshheading:15610235-Recurrence,
pubmed-meshheading:15610235-Steroids
|
pubmed:year |
2005
|
pubmed:articleTitle |
Heparanase activity is dysregulated in children with steroid-sensitive nephrotic syndrome.
|
pubmed:affiliation |
Department of Paediatric Nephrology, Royal Manchester Children's Hospital, Manchester, United Kingdom.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|