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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
Database issue
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pubmed:dateCreated |
2004-12-20
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pubmed:abstractText |
Short interfering RNAs (siRNAs) are a popular method for gene-knockdown, acting by degrading the target mRNA. Before performing experiments it is invaluable to locate and evaluate previous knockdown experiments for the gene of interest. The siRNA database provides a gene-centric view of siRNA experimental data, including siRNAs of known efficacy and siRNAs predicted to be of high efficacy by a combination of methods. Linked to these sequences is information such as siRNA thermodynamic properties and the potential for sequence-specific off-target effects. The database enables the user to evaluate an siRNA's potential for inhibition and non-specific effects. The database is available at http://siRNA.cgb.ki.se.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-10329189,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-11157775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-11253050,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-12360232,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-12519942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-14567917,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-14567918,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-14758366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-14769950,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-15044091,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-15158470,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-15158471,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-15215362,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-15215364,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15608162-15215365
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1362-4962
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
33
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
D131-4
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
2005
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pubmed:articleTitle |
siRNAdb: a database of siRNA sequences.
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pubmed:affiliation |
Center for Genomics and Bioinformatics, Karolinska Institutet, Berzelius väg 35, S-171 77 Stockholm, Sweden. alistair.chalk@cgb.ki.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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