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rdf:type |
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lifeskim:mentions |
umls-concept:C0011860,
umls-concept:C0017337,
umls-concept:C0021641,
umls-concept:C0030685,
umls-concept:C0086418,
umls-concept:C0205419,
umls-concept:C0391871,
umls-concept:C0439849,
umls-concept:C0680255,
umls-concept:C1283071,
umls-concept:C1825292,
umls-concept:C1963578,
umls-concept:C2603343
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pubmed:issue |
1
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pubmed:dateCreated |
2004-12-20
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pubmed:abstractText |
Recently, a novel human G protein-coupled receptor 40 (GPR40), which is predominantly expressed in pancreatic islets, was shown to mediate an amplifying effect of long-chain fatty acids on glucose-induced insulin secretion. The present aim was to examine the coding region of GPR40 for variation and to assess whether identified variants confer an increased risk of Type 2 diabetes or altered insulin release.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0742-3071
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pubmed:author |
pubmed-author:Borch-JohnsenKK,
pubmed-author:GlümerCC,
pubmed-author:HamidY HYH,
pubmed-author:HansenS KSK,
pubmed-author:HansenTT,
pubmed-author:HolstBB,
pubmed-author:JørgensenTT,
pubmed-author:PedersenOO,
pubmed-author:PykeCC,
pubmed-author:SchwartzT WTW,
pubmed-author:UrhammerS ASA,
pubmed-author:VissingHH
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
74-80
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15606695-Case-Control Studies,
pubmed-meshheading:15606695-Diabetes Mellitus, Type 2,
pubmed-meshheading:15606695-Humans,
pubmed-meshheading:15606695-Insulin,
pubmed-meshheading:15606695-Middle Aged,
pubmed-meshheading:15606695-Mutation,
pubmed-meshheading:15606695-Pedigree,
pubmed-meshheading:15606695-Polymorphism, Single Nucleotide,
pubmed-meshheading:15606695-Receptors, G-Protein-Coupled
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pubmed:year |
2005
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pubmed:articleTitle |
Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release.
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pubmed:affiliation |
Steno Diabetes Center, DK-2820 Gentofte, Denmark. yah@steno.dk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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