Source:http://linkedlifedata.com/resource/pubmed/id/15604135
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2005-4-20
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pubmed:abstractText |
We studied whether combined pressure and transesophageal ultrasound monitoring is feasible in the intensive care unit (ICU) setting for global cardiovascular hemodynamic monitoring [systemic vascular resistance (SVR) and total arterial compliance (C(PPM))] and direct estimation of local ascending and descending aortic mechanical properties, i.e., distensibility and compliance coefficients (DC and CC). Pressure-area data were fitted to the arctangent Langewouters model, with aortic cross-sectional area obtained via automated border detection. Data were measured in 19 subjects at baseline, during infusion of sodium nitroprusside (SNP), and after washout. SNP infusion lowered SVR from 1.15 +/- 0.40 to 0.80 +/- 0.32 mmHg.ml(-1).s (P < 0.05), whereas C(PPM) increased from 0.87 +/- 0.46 to 1.02 +/- 0.42 ml/mmHg (P < 0.05). DC and CC increased from 0.0018 +/- 0.0007 to 0.0025 +/- 0.0009 l/mmHg (P < 0.05) and from 0.0066 +/- 0.0028 to 0.0083 +/- 0.0026 cm2/mmHg (P < 0.05), respectively, at the descending, but not ascending, aorta. The Langewouters model fitted the descending aorta data reasonably well. Assessment of local mechanical properties of the human ascending aorta in a clinical setting by automated border detection remains technically challenging.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0363-6135
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
288
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
H2504-11
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15604135-Aged,
pubmed-meshheading:15604135-Aorta, Thoracic,
pubmed-meshheading:15604135-Blood Pressure,
pubmed-meshheading:15604135-Cardiac Output,
pubmed-meshheading:15604135-Coronary Artery Bypass,
pubmed-meshheading:15604135-Echocardiography,
pubmed-meshheading:15604135-Elasticity,
pubmed-meshheading:15604135-Female,
pubmed-meshheading:15604135-Humans,
pubmed-meshheading:15604135-Intensive Care Units,
pubmed-meshheading:15604135-Male,
pubmed-meshheading:15604135-Middle Aged,
pubmed-meshheading:15604135-Models, Cardiovascular,
pubmed-meshheading:15604135-Nitroprusside,
pubmed-meshheading:15604135-Postoperative Care,
pubmed-meshheading:15604135-Vasodilator Agents
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pubmed:year |
2005
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pubmed:articleTitle |
Echocardiographic assessment of aortic elastic properties with automated border detection in an ICU: in vivo application of the arctangent Langewouters model.
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pubmed:affiliation |
Intensive Care Department, Ghent University Hospital, Ghent University, Ghent, Belgium.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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