Linked Life Data

1559755

Source:http://linkedlifedata.com/resource/pubmed/id/1559755

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1992-5-11
pubmed:abstractText
The intensity-response function of the scotopic b-wave of the electroretinogram may be a useful device for monitoring patients with retinal disease. Three models were evaluated that describe this function in 152 patients with diabetic retinopathy of varying severity and in 40 nondiabetic comparison subjects. The models considered were the Naka-Rushton equation fit to all 21 data points collected, the Naka-Rushton equation fit to the data points below the "second limb" of the function, and a log-linear fit only to data at the nine lowest intensities. In addition, the b-wave amplitude at each intensity tested was evaluated individually. Model parameters and amplitude measurements were compared with respect to (1) their ability to distinguish diabetic from nondiabetic subjects determined from the area under the receiver operating characteristic curve and (2) their correlation with retinopathic severity, graded in a standard fashion in fundus photographs. When all the parameters of each model were used in combination, there were no significant differences among the models with either evaluation criterion. Furthermore, b-wave amplitudes at midrange intensities (near -2.2 log cd-sec/m2) did approximately as well as any model.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0146-0404
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1575-83
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Characterization of the electroretinographic scotopic B-wave amplitude in diabetic and normal subjects.
pubmed:affiliation
Biostatistics Center, University of Wisconsin, Madison.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.