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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1992-5-11
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pubmed:abstractText |
We have examined various autoimmunity parameters in AIDS with special emphasis on the expression of pemphigus and bullous pemphigoid antibodies. Sera from healthy seropositive individuals without syphilis (CS-, n = 17), seropositive individuals with syphilis (cs+, n = 11), and patients with AIDS (n = 6) were studied and compared with normal controls (n = 30); autoimmunity parameters related to dermatology were evaluated. Indirect immunofluorescence (IIF) for pemphigus and pemphigoid antibodies, antinuclear antibodies (ANA), anti-DNA antibodies, antismooth muscle antibodies (ASMA) antimitochondrial antibodies (AMA), and antithyroid antibodies (ATA) was carried out and findings were graded with a cumulative index (CI) for each patient group. Pemphigus and bullous pemphigoid-like antibodies (IgG, PV + BP) were detected in 33% of the AIDS patients. Statistically increased CI (P less than 0.01) was found in the CS- group compared with the CS+ group and in the AIDS group compared with CS- (P less than 0.01).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0011-9059
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
113-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1559734-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:1559734-Autoantibodies,
pubmed-meshheading:1559734-Autoimmunity,
pubmed-meshheading:1559734-Fluorescent Antibody Technique,
pubmed-meshheading:1559734-Humans,
pubmed-meshheading:1559734-Immunoglobulin G,
pubmed-meshheading:1559734-Immunoglobulin M,
pubmed-meshheading:1559734-Pemphigoid, Bullous,
pubmed-meshheading:1559734-Pemphigus,
pubmed-meshheading:1559734-Syphilis
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pubmed:year |
1992
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pubmed:articleTitle |
Detection of autoimmunity parameters in the acquired immunodeficiency syndrome (AIDS).
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pubmed:affiliation |
Department of Dermatology, Athens Hospital for Infectious Diseases, Greece.
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pubmed:publicationType |
Journal Article,
Comparative Study
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