|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
2004-12-27
|
|
pubmed:abstractText |
The diluted essential oil of Mentha longifolia (L.) var. chlorodictya Rech F. foliage enhanced the bactericidal activity of nitrofurantoin decreasing the minimum inhibitory concentration (MIC) of nitrofurantoin for nitrofurantoin-resistant strains of Enterobacteriaceae. Thin-layer chromatography (TLC) analysis of the essential oil detected a fraction (R(f) = 0.35, UV lambda(max) of 232.5), which was the most effective in enhancement of nitrofurantoin activity. Using gas liquid chromatography and known standards, the active fraction was identified as piperitone. 1 microl of the piperitone fraction decreased the MIC of nitrofurantoin 3-20 fold for the different strains of Enterobacteriaceae tested.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0951-418X
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright 2004 John Wiley & Sons, Ltd.
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
18
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
911-4
|
|
pubmed:meshHeading |
pubmed-meshheading:15597306-Anti-Bacterial Agents,
pubmed-meshheading:15597306-Anti-Infective Agents, Urinary,
pubmed-meshheading:15597306-Drug Interactions,
pubmed-meshheading:15597306-Drug Resistance, Bacterial,
pubmed-meshheading:15597306-Enterobacteriaceae,
pubmed-meshheading:15597306-Humans,
pubmed-meshheading:15597306-Mentha,
pubmed-meshheading:15597306-Microbial Sensitivity Tests,
pubmed-meshheading:15597306-Monoterpenes,
pubmed-meshheading:15597306-Nitrofurantoin,
pubmed-meshheading:15597306-Phytotherapy,
pubmed-meshheading:15597306-Plant Oils
|
|
pubmed:year |
2004
|
|
pubmed:articleTitle |
Piperitone from Mentha longifolia var. chorodictya Rech F. reduces the nitrofurantoin resistance of strains of enterobacteriaceae.
|
|
pubmed:affiliation |
Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. shahverd@sina.tums.ac.ir
|
|
pubmed:publicationType |
Journal Article
|
