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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2004-12-15
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pubmed:abstractText |
A wide spectrum of extraglandular manifestations may occur in patients with Sjogren's syndrome (SS), but the mechanisms responsible for in vivo progression are still obscure. We undertook this study to evaluate the age-related changes during the development of extraglandular autoimmune lesions, including arthritis, in the murine model of primary SS, and to evaluate the possible relationship between age-related disturbance of activation-induced cell death and the in vivo kinetics against autoantigens.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0004-3591
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3974-84
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15593201-Aging,
pubmed-meshheading:15593201-Animals,
pubmed-meshheading:15593201-Apoptosis,
pubmed-meshheading:15593201-Arthritis, Rheumatoid,
pubmed-meshheading:15593201-Autoantigens,
pubmed-meshheading:15593201-Bystander Effect,
pubmed-meshheading:15593201-Carrier Proteins,
pubmed-meshheading:15593201-Cell Proliferation,
pubmed-meshheading:15593201-Culture Media, Conditioned,
pubmed-meshheading:15593201-Cytokines,
pubmed-meshheading:15593201-Disease Models, Animal,
pubmed-meshheading:15593201-Female,
pubmed-meshheading:15593201-Joints,
pubmed-meshheading:15593201-Lymphocyte Activation,
pubmed-meshheading:15593201-Matrix Metalloproteinase 9,
pubmed-meshheading:15593201-Mice,
pubmed-meshheading:15593201-Mice, Mutant Strains,
pubmed-meshheading:15593201-Microfilament Proteins,
pubmed-meshheading:15593201-Sjogren's Syndrome,
pubmed-meshheading:15593201-T-Lymphocytes
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pubmed:year |
2004
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pubmed:articleTitle |
Development of autoimmune arthritis with aging via bystander T cell activation in the mouse model of Sjögren's syndrome.
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pubmed:affiliation |
Tokushima University School of Dentistry, and The University of Tokushima School of Medicine, Tokushima, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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