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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-6-2
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pubmed:abstractText |
Brain tissue oxygen pressure (PbtO2) correlates to cerebral blood flow (CBF) during spontaneous circulation, with one important regulator being nitric oxide (NO). Although it is established that arginine vasopressin (AVP) improves CBF and global cerebral oxygenation during cardiopulmonary resuscitation, it is unknown whether similar beneficial effects are present during spontaneous circulation. The purpose of this study was to investigate the effects of AVP with and without pre-treatment with the NO synthase inhibitor N-omega-nitro-L-arginine methyl ester (L-NAME) on local brain tissue oxygenation in a beating heart model.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0001-6268
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
147
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-90; discussion 290
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:15592883-Animals,
pubmed-meshheading:15592883-Anoxia,
pubmed-meshheading:15592883-Arginine Vasopressin,
pubmed-meshheading:15592883-Brain,
pubmed-meshheading:15592883-Cerebral Arteries,
pubmed-meshheading:15592883-Cerebrovascular Circulation,
pubmed-meshheading:15592883-Drug Interactions,
pubmed-meshheading:15592883-Enzyme Inhibitors,
pubmed-meshheading:15592883-Female,
pubmed-meshheading:15592883-Heart Arrest,
pubmed-meshheading:15592883-Hypoxia-Ischemia, Brain,
pubmed-meshheading:15592883-Male,
pubmed-meshheading:15592883-Models, Animal,
pubmed-meshheading:15592883-NG-Nitroarginine Methyl Ester,
pubmed-meshheading:15592883-Neuroprotective Agents,
pubmed-meshheading:15592883-Nitric Oxide,
pubmed-meshheading:15592883-Nitric Oxide Donors,
pubmed-meshheading:15592883-Nitric Oxide Synthase,
pubmed-meshheading:15592883-Oxygen,
pubmed-meshheading:15592883-Oxygen Consumption,
pubmed-meshheading:15592883-Sus scrofa,
pubmed-meshheading:15592883-Vasodilator Agents
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pubmed:year |
2005
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pubmed:articleTitle |
Changes of local brain tissue oxygen pressure after vasopressin during spontaneous circulation.
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pubmed:affiliation |
Department of Anaesthesiology and Intensive Care Medicine, University Hospital Schleswig-Holstein, Campus Kiel, Germany. e.cavus@t-online.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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