Source:http://linkedlifedata.com/resource/pubmed/id/15588066
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2004-12-13
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pubmed:abstractText |
The presence of antiphospholipid antibodies in plasma is a risk factor for thromboembolic complications. In vitro, however, the same antibodies can prolong dotting times in coagulation assays, a classic marker for a bleeding tendency. For years this contradiction has puzzled many scientists. Recently new insights into the interaction between antiphospholipid antibodies and their main target, the protein beta-2-glycoprotein I, have opened new avenues for the understanding of the pathology of this syndrome.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0300-2977
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
267-72
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15588066-Antibodies, Antiphospholipid,
pubmed-meshheading:15588066-Antiphospholipid Syndrome,
pubmed-meshheading:15588066-Blood Coagulation Tests,
pubmed-meshheading:15588066-Glycoproteins,
pubmed-meshheading:15588066-Humans,
pubmed-meshheading:15588066-Risk Factors,
pubmed-meshheading:15588066-Thromboembolism,
pubmed-meshheading:15588066-beta 2-Glycoprotein I
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pubmed:year |
2004
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pubmed:articleTitle |
Pathophysiology of antiphospholipid antibodies.
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pubmed:affiliation |
Department of Haematology, Room G03.647, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands. ph.g.degroot@azu.nl
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pubmed:publicationType |
Journal Article,
Review
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