rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
11
|
pubmed:dateCreated |
2004-12-13
|
pubmed:abstractText |
Enalapril may undergo the thermal-induced intramolecular interaction to cause an enalapril diketopiperazine (DKP) formation. It is interesting to study the influence of Eudragit E, as a coating polymer, on the stability of enalapril maleate. The reaction kinetics of the solid-state degradation process of pure enalapril maleate and Eudragit E/enalapril maleate mixture with different weight ratios were examined. The mechanism of solid-state interaction between Eudragit E and enalapril maleate was also discussed.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0724-8741
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
21
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2127-32
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:15587937-Algorithms,
pubmed-meshheading:15587937-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:15587937-Diketopiperazines,
pubmed-meshheading:15587937-Enalapril,
pubmed-meshheading:15587937-Excipients,
pubmed-meshheading:15587937-Kinetics,
pubmed-meshheading:15587937-Maleates,
pubmed-meshheading:15587937-Methacrylates,
pubmed-meshheading:15587937-Piperazines,
pubmed-meshheading:15587937-Spectroscopy, Fourier Transform Infrared
|
pubmed:year |
2004
|
pubmed:articleTitle |
Eudragit E accelerated the diketopiperazine formation of enalapril maleate determined by thermal FTIR microspectroscopic technique.
|
pubmed:affiliation |
Department of Applied Chemistry, National ChiaYi University, ChiaYi, Taiwan, Republic of China.
|
pubmed:publicationType |
Journal Article
|