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rdf:type |
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lifeskim:mentions |
umls-concept:C0010346,
umls-concept:C0017431,
umls-concept:C0332281,
umls-concept:C0449258,
umls-concept:C0449432,
umls-concept:C0521117,
umls-concept:C0599840,
umls-concept:C1179435,
umls-concept:C1524073,
umls-concept:C1548799,
umls-concept:C1705248,
umls-concept:C1826449,
umls-concept:C2698415
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pubmed:issue |
12
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pubmed:dateCreated |
2004-12-1
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pubmed:abstractText |
Antibodies directed against the porin protein C of Escherichia coli (anti-OmpC) and Pseudomonas fluorescens (anti-I2) have recently been described in Crohn's disease (CD). Those directed against Saccharomyces cerevisiae (ASCA) and the perinuclear component of neutrophils (pANCA) have been more widely studied and may be of diagnostic importance. We aimed to assess the frequency of anti-OmpC, anti-I2, ASCA, and pANCA, in an independent Scottish CD cohort, establish phenotypic associations, and compare with a U.S. cohort.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0002-9270
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
99
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2376-84
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pubmed:dateRevised |
2008-5-13
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pubmed:meshHeading |
pubmed-meshheading:15571586-Adolescent,
pubmed-meshheading:15571586-Adult,
pubmed-meshheading:15571586-Aged,
pubmed-meshheading:15571586-Aged, 80 and over,
pubmed-meshheading:15571586-Antibodies, Bacterial,
pubmed-meshheading:15571586-Antigens, Bacterial,
pubmed-meshheading:15571586-Chi-Square Distribution,
pubmed-meshheading:15571586-Crohn Disease,
pubmed-meshheading:15571586-Disease Progression,
pubmed-meshheading:15571586-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15571586-Female,
pubmed-meshheading:15571586-Genotype,
pubmed-meshheading:15571586-Humans,
pubmed-meshheading:15571586-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:15571586-Male,
pubmed-meshheading:15571586-Middle Aged,
pubmed-meshheading:15571586-Nod2 Signaling Adaptor Protein,
pubmed-meshheading:15571586-Saccharomyces cerevisiae,
pubmed-meshheading:15571586-Severity of Illness Index,
pubmed-meshheading:15571586-Statistics, Nonparametric
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pubmed:year |
2004
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pubmed:articleTitle |
Sero-reactivity to microbial components in Crohn's disease is associated with disease severity and progression, but not NOD2/CARD15 genotype.
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pubmed:affiliation |
Gastrointestinal Unit, University of Edinburgh Department of Medical Sciences, School of Clinical and Molecular Medicine, Western General Hospital, Edinburgh EH4 2XU, UK.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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