Source:http://linkedlifedata.com/resource/pubmed/id/15570744
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2004-12-1
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| pubmed:abstractText |
This study was conducted to compare the safety of soybean meal prepared from genetically modified (GM) glyphosate-tolerant (Roundup Ready; RR) soybeans and conventional soybeans. Eighty Sprague-Dawley rats (40 males and 40 females) were randomly allotted to one of four groups according to sex and body weight for a 13-week feeding experiment. The rats were fed corn-based diets containing 60% conventional soybean meal, a mixture of 30% conventional and 30% RR soybean meal, 60% or 90% RR soybean meal. All diets were adjusted to an identical nutrient level except the 90% RR diet. The two soybean meals were similar in chemical analysis and amino acid composition. During the 13-week growth trial, body weight (P < 0.05) and feed intake (P < 0.05) decreased only in rats fed with 90% RR soybean meal at the first week. No treatment-related deaths occurred during the experiment. Gross necropsy findings, haematological or urinalysis values and clinical serum parameters showed no meaningful differences between rats fed the control and RR soybean meals. A 145 bp of cp4 epsps gene specific for the GM constructs from RR soybean meal or a 407 bp of lec gene from endogenous soybean DNA could not be detected in investigated masseter muscle samples. No adverse effects of glyphosate-tolerant soybean meal on rats were seen even at levels as high as 90% of the diet.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Aug
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| pubmed:issn |
1745-039X
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
58
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
295-310
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| pubmed:dateRevised |
2008-11-21
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| pubmed:meshHeading |
pubmed-meshheading:15570744-Animal Feed,
pubmed-meshheading:15570744-Animal Nutritional Physiological Phenomena,
pubmed-meshheading:15570744-Animals,
pubmed-meshheading:15570744-Blood Chemical Analysis,
pubmed-meshheading:15570744-DNA, Plant,
pubmed-meshheading:15570744-Dose-Response Relationship, Drug,
pubmed-meshheading:15570744-Energy Intake,
pubmed-meshheading:15570744-Female,
pubmed-meshheading:15570744-Male,
pubmed-meshheading:15570744-Nutrition Assessment,
pubmed-meshheading:15570744-Plants, Genetically Modified,
pubmed-meshheading:15570744-Random Allocation,
pubmed-meshheading:15570744-Rats,
pubmed-meshheading:15570744-Rats, Sprague-Dawley,
pubmed-meshheading:15570744-Safety,
pubmed-meshheading:15570744-Soybean Proteins,
pubmed-meshheading:15570744-Soybeans,
pubmed-meshheading:15570744-Urinalysis,
pubmed-meshheading:15570744-Weight Gain
|
| pubmed:year |
2004
|
| pubmed:articleTitle |
Nutritional assessment and fate of DNA of soybean meal from roundup ready or conventional soybeans using rats.
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| pubmed:affiliation |
National Feed Engineering Technology Research Center, China Agricultural University, Beijing, China.
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| pubmed:publicationType |
Journal Article
|