Source:http://linkedlifedata.com/resource/pubmed/id/15569170
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2004-11-30
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pubmed:abstractText |
We present the case of a 61-year-old man with severe haemophilia A and a high-titre factor VIII inhibitor who underwent successful orthotopic liver transplantation (OLT) for hepatocellular carcinoma. Postoperatively, a modest early anamnestic response to FVIII was followed by immunological tolerance to FVIII. This case illustrates the technical feasibility of OLT in some patients with high-titre inhibitors to FVIII, and suggests that immune tolerance may be induced by endogenously produced FVIII from the transplanted organ.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1351-8216
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
735-7
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pubmed:dateRevised |
2009-10-21
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pubmed:meshHeading |
pubmed-meshheading:15569170-Blood Loss, Surgical,
pubmed-meshheading:15569170-Factor VIII,
pubmed-meshheading:15569170-Feasibility Studies,
pubmed-meshheading:15569170-Hemophilia A,
pubmed-meshheading:15569170-Hepatitis C, Chronic,
pubmed-meshheading:15569170-Humans,
pubmed-meshheading:15569170-Liver Transplantation,
pubmed-meshheading:15569170-Male,
pubmed-meshheading:15569170-Middle Aged
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pubmed:year |
2004
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pubmed:articleTitle |
Successful liver transplantation in a patient with severe haemophilia A and a high-titre factor VIII inhibitor.
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pubmed:affiliation |
Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
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