Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2004-11-30
pubmed:abstractText
We present the case of a 61-year-old man with severe haemophilia A and a high-titre factor VIII inhibitor who underwent successful orthotopic liver transplantation (OLT) for hepatocellular carcinoma. Postoperatively, a modest early anamnestic response to FVIII was followed by immunological tolerance to FVIII. This case illustrates the technical feasibility of OLT in some patients with high-titre inhibitors to FVIII, and suggests that immune tolerance may be induced by endogenously produced FVIII from the transplanted organ.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1351-8216
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
735-7
pubmed:dateRevised
2009-10-21
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Successful liver transplantation in a patient with severe haemophilia A and a high-titre factor VIII inhibitor.
pubmed:affiliation
Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
pubmed:publicationType
Journal Article, Case Reports