Source:http://linkedlifedata.com/resource/pubmed/id/15569168
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
2004-11-30
|
| pubmed:abstractText |
Patients with haemophilia are at increased risk of hepatitis C infection because of prior transfusion of blood products. Virtually all haemophiliacs who received pooled blood products before the mid-1980s have been infected with hepatitis C. A liver biopsy is important to identify the extent of liver disease, and to help determine the necessity of interferon therapy. With factor replacement, in-hospital liver biopsy is safe. Thirty patients with haemophilia were evaluated for chronic hepatitis C infection. Eleven patients subsequently underwent successful transjugular liver biopsy in the outpatient setting after appropriate factor replacement. Mean +/- SD pre- and posthaemoglobin values were 15.8 +/- 0.79 and 14.4 +/- 0.71 g dL(-1) (P = ns). There was no significant change in heart rate, systolic or diastolic blood pressure during the monitoring period (P = ns) and no major complication was noted in perioperative follow-up. The mean length of the liver biopsy specimens was 1.7 +/- 0.3 cm, mean grade was 2 +/- 0.6 and mean stage was 2.3 +/- 1.2. Our experience demonstrates that outpatient transjugular liver biopsy can be safely performed in patients with haemophilia in the outpatient setting, avoiding the cost and need for hospital admission.
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| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
1351-8216
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
10
|
| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
727-31
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| pubmed:dateRevised |
2009-10-21
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| pubmed:meshHeading |
pubmed-meshheading:15569168-Adult,
pubmed-meshheading:15569168-Ambulatory Surgical Procedures,
pubmed-meshheading:15569168-Biopsy,
pubmed-meshheading:15569168-Factor IX,
pubmed-meshheading:15569168-Factor VIII,
pubmed-meshheading:15569168-Hemophilia A,
pubmed-meshheading:15569168-Hepatitis C, Chronic,
pubmed-meshheading:15569168-Humans,
pubmed-meshheading:15569168-Liver,
pubmed-meshheading:15569168-Male,
pubmed-meshheading:15569168-Postoperative Complications
|
| pubmed:year |
2004
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| pubmed:articleTitle |
Same day outpatient transjugular liver biopsies in haemophilia.
|
| pubmed:affiliation |
Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA. ssaab@mednet.ucla.edu
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| pubmed:publicationType |
Journal Article
|