Linked Life Data

1556840

Source:http://linkedlifedata.com/resource/pubmed/id/1556840

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1992-5-7
pubmed:abstractText
We have reported that sexual behavior of male rats is impaired by long-term psychological stress. We measured dopamine (DA) and its metabolites (3,4-dihydroxyphenylacetic acid, DOPAC, and homovanillic acid, HVA) in the brain of rats which were exposed to the long-term stress. Our experiment was focused on the medial preoptic area (MPOA), which is perhaps the single most critical area of the brain mediating sexual behavior, the amygdala, the substantia nigra, the striatum, the nucleus accumbens and the cortex. In the MPOA, dopamine, DOPAC, and HVA decreased; in the substantia nigra and amygdala, dopamine and HVA decreased; and in the striatum and nucleus accumbens only HVA decreased after long-term psychological stress. In the cortex, however, no evidence of change was recognized. These changes indicate low activity of dopamine neurons which have an important role in male sexual behavior. Therefore, we suspect that exposure of male rats to psychological stress leads to a decrease in the activity of dopamine neurons, especially in the MPOA, amygdala, and substantia nigra, impairing their sexual behavior.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0021-5287
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
212-9
pubmed:dateRevised
2011-7-28
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
[Psychological stress and sexual behavior in male rats. II. Effect of psychological stress on dopamine and its metabolites in the critical brain areas mediating sexual behavior].
pubmed:affiliation
Department of Urology, Sapporo Medical College.
pubmed:publicationType
Journal Article, English Abstract