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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1992-5-7
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pubmed:abstractText |
A retrospective analysis of 70 patients with primary malignant lymphoma of the thyroid treated at this institute between 1965-1983 has been conducted. The clinicopathological features and prognostic factors have been studied. The mean age was 67.5 years and there was a marked female:male ratio of 8:1. A total of 32 (45.7%) Stage IE and 38 (54.3%) Stage IIE patients were identified. In 64 cases histological material was reviewed and classified employing the Kiel classification. All the tumors were of B cell lineage and the majority were follicle center cell type. A biopsy only was performed in 27 patients, lobectomy in 11 patients, subtotal thyroidectomy in 27 and macroscopic thyroidectomy in 5 patients. All patients were treated with radiotherapy. The overall 5-year survival was 42%, with 63% for Stage IE and 27% for Stage IIE. The corrected overall 5-year survival was 49% with 68% for Stage IE and 36% for Stage IIE. The corresponding overall relapse free survival was 42% with 60% for Stage IE, and 31% for Stage IIE. Factors of prognostic significance for relapse and survival were stage, radiotherapy dose, stridor, retrosternal extension and fixation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0360-3016
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
929-33
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1555984-Adult,
pubmed-meshheading:1555984-Aged,
pubmed-meshheading:1555984-Aged, 80 and over,
pubmed-meshheading:1555984-Combined Modality Therapy,
pubmed-meshheading:1555984-England,
pubmed-meshheading:1555984-Female,
pubmed-meshheading:1555984-Humans,
pubmed-meshheading:1555984-Lymphoma, B-Cell,
pubmed-meshheading:1555984-Male,
pubmed-meshheading:1555984-Middle Aged,
pubmed-meshheading:1555984-Prognosis,
pubmed-meshheading:1555984-Retrospective Studies,
pubmed-meshheading:1555984-Survival Rate,
pubmed-meshheading:1555984-Thyroid Neoplasms
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pubmed:year |
1992
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pubmed:articleTitle |
Primary malignant lymphoma of the thyroid: a clinicopathological analysis.
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pubmed:affiliation |
Department of Radiotherapy and Oncology, Christie Hospital and Holt Radium Institute, Manchester, U.K.
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pubmed:publicationType |
Journal Article
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