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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2004-11-19
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pubmed:abstractText |
Sarcoidosis is immunologically characterized by highly enhanced Th1 responses in active stage. TAK-603 is a new quinoline derivative, which selectively suppresses Th1 cytokine production. Thus, the present study was designed to investigate whether TAK-603 ameliorates excess IFN-gamma production in active sarcoidosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1124-0490
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
204-11
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:15554077-Adult,
pubmed-meshheading:15554077-Case-Control Studies,
pubmed-meshheading:15554077-Female,
pubmed-meshheading:15554077-Humans,
pubmed-meshheading:15554077-Inflammation,
pubmed-meshheading:15554077-Interferon-gamma,
pubmed-meshheading:15554077-Interleukin-12,
pubmed-meshheading:15554077-Interleukin-18,
pubmed-meshheading:15554077-Leukocytes, Mononuclear,
pubmed-meshheading:15554077-Male,
pubmed-meshheading:15554077-Middle Aged,
pubmed-meshheading:15554077-Quinolines,
pubmed-meshheading:15554077-Sarcoidosis,
pubmed-meshheading:15554077-T-Lymphocytes,
pubmed-meshheading:15554077-Triazoles
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pubmed:year |
2004
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pubmed:articleTitle |
T helper 1 inhibitor TAK-603 inhibits IFN-gamma and IL-12 production with no effect on IL-18: an observation in sarcoidosis patients.
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pubmed:affiliation |
Department of Respiratory Medicine, Sapporo Hospital, Hokkaido Railway Company, Japan.
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pubmed:publicationType |
Journal Article
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