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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2005-1-25
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pubmed:abstractText |
Iron (Fe) can cause tissue injury and oxidative stress by catalyzing hydroxyl radical production and lipid peroxidation. Intravenous (i.v.) Fe preparations are routinely administered to treat anemia in patients with chronic renal failure (CRF), a condition marked by oxidative stress and inflammation. In an earlier study, we showed that iron overload augments oxidative stress in the cardiovascular tissues of CRF rats. This study was designed to expand these observations to other major organs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-8095
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2004 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
569-75
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pubmed:dateRevised |
2007-2-14
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pubmed:meshHeading |
pubmed-meshheading:15550752-Animals,
pubmed-meshheading:15550752-Antioxidants,
pubmed-meshheading:15550752-Catalase,
pubmed-meshheading:15550752-Glutathione Peroxidase,
pubmed-meshheading:15550752-Injections, Intravenous,
pubmed-meshheading:15550752-Iron,
pubmed-meshheading:15550752-Kidney Failure, Chronic,
pubmed-meshheading:15550752-Male,
pubmed-meshheading:15550752-NADPH Oxidase,
pubmed-meshheading:15550752-Nephrectomy,
pubmed-meshheading:15550752-Oxidative Stress,
pubmed-meshheading:15550752-Phosphoproteins,
pubmed-meshheading:15550752-Rats,
pubmed-meshheading:15550752-Rats, Sprague-Dawley,
pubmed-meshheading:15550752-Superoxide Dismutase
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pubmed:articleTitle |
Iron and oxidative stress in renal insufficiency.
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pubmed:affiliation |
Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Boramae Hospital, Seoul, Korea. sclimjy@snu.ac.kr
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pubmed:publicationType |
Journal Article
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