Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2004-12-16
pubmed:abstractText
The etiology of the Mayer-Rokitanski-Kuster-Hauser (MRKH) syndrome, where congenitally the Mullerian ducts fail to develop into the uterus, cervix and upper vagina, along with other malformations, is unresolved. Anti-Mullerian hormone (AMH) signal transduction inducing the degradation of Mullerian ducts in males is implicated in the MRKH syndrome. This study examined if DNA sequence variations are responsible for the activation of AMH and aberrant hormone levels in MRKH patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0268-1161
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
149-57
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:15550498-Abnormalities, Multiple, pubmed-meshheading:15550498-Adolescent, pubmed-meshheading:15550498-Adult, pubmed-meshheading:15550498-Alleles, pubmed-meshheading:15550498-Anti-Mullerian Hormone, pubmed-meshheading:15550498-Ascitic Fluid, pubmed-meshheading:15550498-Base Sequence, pubmed-meshheading:15550498-Case-Control Studies, pubmed-meshheading:15550498-DNA, pubmed-meshheading:15550498-Exons, pubmed-meshheading:15550498-Female, pubmed-meshheading:15550498-Gene Expression, pubmed-meshheading:15550498-Genetic Variation, pubmed-meshheading:15550498-Genitalia, Female, pubmed-meshheading:15550498-Glycoproteins, pubmed-meshheading:15550498-Humans, pubmed-meshheading:15550498-Middle Aged, pubmed-meshheading:15550498-Mullerian Ducts, pubmed-meshheading:15550498-Nucleoproteins, pubmed-meshheading:15550498-Phenotype, pubmed-meshheading:15550498-Promoter Regions, Genetic, pubmed-meshheading:15550498-RNA-Binding Proteins, pubmed-meshheading:15550498-Syndrome, pubmed-meshheading:15550498-Testicular Hormones
pubmed:year
2005
pubmed:articleTitle
DNA sequence variations of the entire anti-Mullerian hormone (AMH) gene promoter and AMH protein expression in patients with the Mayer-Rokitanski-Kuster-Hauser syndrome.
pubmed:affiliation
Department of Gynaecology and Obstetrics and Department of Biochemistry at the University of Erlangen-Nuremberg, Erlangen, Germany.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't