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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2004-11-19
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pubmed:abstractText |
Interferons (IFN) are currently being used to treat melanoma, including some patients with uveal melanoma. IFN is thought to inhibit tumour growth through downregulation of the c-myc oncogene; the overexpression of which has been shown to be associated with resistance in cell lines. The aim of this study was to investigate the relation between c-myc gene expression and IFN sensitivity in a series of uveal melanomas in a short term chemosensitivity assay.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-10434891,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-10477162,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-10661768,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-10919885,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-10922203,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-11420751,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-11527924,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-11919239,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-12039519,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-12373596,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-12382524,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-12436444,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-1586975,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-1706617,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-2023760,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-2453829,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-3338074,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-3402430,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-3785169,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-3860831,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-7488605,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-7670137,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-7762413,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-8558223,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-8618233,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-8783648,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9038509,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9072006,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9261748,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9396619,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9422944,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9462382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9505825,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9552047,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9583686,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9610866,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9664877,
http://linkedlifedata.com/resource/pubmed/commentcorrection/15548813-9849406
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0007-1161
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1563-7
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15548813-Adult,
pubmed-meshheading:15548813-Age Factors,
pubmed-meshheading:15548813-Aged,
pubmed-meshheading:15548813-Aged, 80 and over,
pubmed-meshheading:15548813-Antineoplastic Agents,
pubmed-meshheading:15548813-Dose-Response Relationship, Drug,
pubmed-meshheading:15548813-Female,
pubmed-meshheading:15548813-Flow Cytometry,
pubmed-meshheading:15548813-Gene Expression,
pubmed-meshheading:15548813-Humans,
pubmed-meshheading:15548813-Interferon-alpha,
pubmed-meshheading:15548813-Male,
pubmed-meshheading:15548813-Melanoma,
pubmed-meshheading:15548813-Middle Aged,
pubmed-meshheading:15548813-Proto-Oncogene Proteins c-myc,
pubmed-meshheading:15548813-Recombinant Proteins,
pubmed-meshheading:15548813-Tumor Cells, Cultured,
pubmed-meshheading:15548813-Uveal Neoplasms
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pubmed:year |
2004
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pubmed:articleTitle |
The relation between c-myc expression and interferon sensitivity in uveal melanoma.
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pubmed:affiliation |
RAFT Institute of Plastic Surgery, Mount Vernon Hospital, Northwood, Middlesex HA6 2JR, UK. paultulley@hotmail.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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