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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1992-5-7
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pubmed:abstractText |
Aldicarb toxicosis was diagnosed in 200 sheep that died suddenly. Carbamate insecticide toxicosis was suspected based on observed clinical signs (hypersalivation, diarrhea, urination, paddling, seizures, miosis, and deaths occurring within 1 hour). Tissue samples were submitted from 4 Columbian ewes for pathologic and analytical evaluation. Severe diffuse pulmonary edema was observed on gross and histologic examination. Inhibition of cholinesterase activity in retina (21.2-68.1% of normal activity, n = 3), brain (40.6-45.6% of normal activity, n = 3), and whole blood (27% of normal activity, n = 1) supported a diagnosis of carbamate toxicosis. Reversal of brain and whole blood cholinesterase activities (reactivation factor greater than 1.4) following an in vitro 1 hour incubation at 37 C was also consistent with carbamate poisoning. Aldicarb toxicosis was confirmed following its detection in rumen contents at 1.5, 5.5, and 334 ppm using both high-pressure liquid chromatography with UV detection and gas chromatography with nitrogen/phosphorus detection.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1040-6387
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
45-7
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1554768-Acetylcholinesterase,
pubmed-meshheading:1554768-Aldicarb,
pubmed-meshheading:1554768-Animals,
pubmed-meshheading:1554768-Brain,
pubmed-meshheading:1554768-Death, Sudden,
pubmed-meshheading:1554768-Female,
pubmed-meshheading:1554768-Gastrointestinal Contents,
pubmed-meshheading:1554768-Poisoning,
pubmed-meshheading:1554768-Pulmonary Edema,
pubmed-meshheading:1554768-Retina,
pubmed-meshheading:1554768-Rumen,
pubmed-meshheading:1554768-Sheep,
pubmed-meshheading:1554768-Sheep Diseases
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pubmed:year |
1992
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pubmed:articleTitle |
Aldicarb toxicosis in a flock of sheep.
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pubmed:affiliation |
University of Illinois, Laboratories of Veterinary Diagnostic Medicine, College of Veterinary Medicine, Urbana 61801.
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pubmed:publicationType |
Journal Article
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