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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-1-5
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pubmed:abstractText |
Prolonged lithium treatment may induce progressive deterioration of renal function in humans and experimental animals. N-Acetylcysteine (NAC) has been shown to be effective in the prevention of hypoperfusion and toxin-induced renal failure, but its effect on lithium nephrotoxicity has not been evaluated yet. The purpose of this study was to examine a possible renoprotective effect of NAC against lithium-induced renal failure in a rat model.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0931-0509
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
65-70
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:15546888-Acetylcysteine,
pubmed-meshheading:15546888-Animals,
pubmed-meshheading:15546888-Biopsy, Needle,
pubmed-meshheading:15546888-Disease Models, Animal,
pubmed-meshheading:15546888-Dose-Response Relationship, Drug,
pubmed-meshheading:15546888-Glomerular Filtration Rate,
pubmed-meshheading:15546888-Immunohistochemistry,
pubmed-meshheading:15546888-Injections, Intraperitoneal,
pubmed-meshheading:15546888-Kidney Function Tests,
pubmed-meshheading:15546888-Lithium,
pubmed-meshheading:15546888-Male,
pubmed-meshheading:15546888-Probability,
pubmed-meshheading:15546888-Random Allocation,
pubmed-meshheading:15546888-Rats,
pubmed-meshheading:15546888-Rats, Sprague-Dawley,
pubmed-meshheading:15546888-Reference Values,
pubmed-meshheading:15546888-Renal Insufficiency,
pubmed-meshheading:15546888-Sensitivity and Specificity
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pubmed:year |
2005
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pubmed:articleTitle |
N-Acetylcysteine ameliorates lithium-induced renal failure in rats.
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pubmed:affiliation |
Department of Medicine A, Assaf Harofeh Medical Center, Zerifin, Israel. efratishai@013.net.il
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pubmed:publicationType |
Journal Article,
Comparative Study
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