GENERIC 15546179

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0028953, umls-concept:C0220781, umls-concept:C1883254
pubmed:issue	6
pubmed:dateCreated	2004-11-19
pubmed:abstractText	A solid-phase synthesis for phosphate-branched oligonucleotides is described. The method is based on coupling of a single nucleoside phosphorodiamidite to terminal hydroxyl functions of two solid-supported oligonucleotides. After oxidation of the phosphite triester obtained to a phosphate triester, the third branch is assembled by conventional phosphoramidite chemistry.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9010319
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Oligonucleotides, http://linkedlifedata.com/resource/pubmed/chemical/Phosphates
pubmed:status	MEDLINE
pubmed:issn	1043-1802
pubmed:author	pubmed-author:HeinonenPetriP, pubmed-author:LönnbergHarriH
pubmed:issnType	Print
pubmed:volume	15
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1158-60
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:15546179-Oligonucleotides, pubmed-meshheading:15546179-Phosphates
pubmed:articleTitle	Synthesis of phosphate-branched oligonucleotides.
pubmed:affiliation	Department of Chemistry, University of Turku, FIN-20014 Turku, Finland. petheino@utu.fi
pubmed:publicationType	Journal Article, Review, Research Support, Non-U.S. Gov't