Linked Life Data

1554452

Source:http://linkedlifedata.com/resource/pubmed/id/1554452

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1992-5-7
pubmed:abstractText
In this study, the summating potential (SP) and action potential (AP) amplitude ratio was measured in 15 guinea pigs before and after surgical induction of a round window fistula. The round window fistula was then allowed to heal, and recordings were obtained after 1 month. Stimuli included 8000-Hz and 2000-Hz tone bursts and click stimuli at levels ranging from 100-dB peak equivalent sound pressure level to AP threshold. Immediately after fistula induction, a statistically significant enlargement in the SP/AP amplitude ratio occurred in response to the click and the 8000-Hz tone-burst stimuli. No change in the SP/AP amplitude ratio was observed for the 2000-Hz stimuli. After healing, the SP/AP amplitude ratio generally returned to prelesion values. No unhealed perilymphatic fistulas were observed in any of the 15 guinea pigs at 1 month after fistula induction. Considering the difficulty of diagnosing perilymphatic fistula in humans, it is encouraging to note that, at least in animals, noninvasive electrophysiologic recordings may perhaps be sensitive to the presence of patent perilymphatic fistula.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0886-4470
pubmed:author
pubmed:issnType
Print
pubmed:volume
118
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
301-4
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Electrocochleographic recordings in acute and healed perilymphatic fistula.
pubmed:affiliation
Department of Surgery, Southern Illinois University School of Medicine, Springfield.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.