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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2004-11-12
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pubmed:abstractText |
Posttranscriptional modification involving phosphorylation of wild-type p53 has been considered to play a role in the stabilization of p53. Little is known, however, about the role of phosphorylation of mutant p53 overexpressed in tumors. The aim of this study is to determine the phosphorylation state of p53 in tumors and its contribution to tumor development.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0030-2414
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pubmed:author |
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pubmed:copyrightInfo |
2004 S. Karger AG, Basel.
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pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
143-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15539919-Adult,
pubmed-meshheading:15539919-Aged,
pubmed-meshheading:15539919-Aged, 80 and over,
pubmed-meshheading:15539919-Apoptosis,
pubmed-meshheading:15539919-Carcinoma, Squamous Cell,
pubmed-meshheading:15539919-Cell Cycle Proteins,
pubmed-meshheading:15539919-Cell Proliferation,
pubmed-meshheading:15539919-Disease Progression,
pubmed-meshheading:15539919-Esophageal Neoplasms,
pubmed-meshheading:15539919-Female,
pubmed-meshheading:15539919-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:15539919-Humans,
pubmed-meshheading:15539919-Ki-67 Antigen,
pubmed-meshheading:15539919-Lymphatic Metastasis,
pubmed-meshheading:15539919-Male,
pubmed-meshheading:15539919-Middle Aged,
pubmed-meshheading:15539919-Multivariate Analysis,
pubmed-meshheading:15539919-Phosphorylation,
pubmed-meshheading:15539919-Predictive Value of Tests,
pubmed-meshheading:15539919-Prognosis,
pubmed-meshheading:15539919-Proportional Hazards Models,
pubmed-meshheading:15539919-Serine,
pubmed-meshheading:15539919-Tumor Suppressor Protein p53,
pubmed-meshheading:15539919-Up-Regulation
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pubmed:year |
2004
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pubmed:articleTitle |
Prognostic significance of serine 392 phosphorylation in overexpressed p53 protein in human esophageal squamous cell carcinoma.
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pubmed:affiliation |
Department of Tumor Pathology, Kochi University, Nankoku, Kochi, Japan. manabu@med.kochi-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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