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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2004-12-31
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pubmed:abstractText |
Endothelial lipase (EL) is a vascular phospholipase that hydrolyzes high-density lipoprotein (HDL) as its preferred substrate. Scavenger receptor-class B type I (SR-BI) is an HDL receptor that mediates the selective uptake of cholesteryl ester. This study investigates the role of EL and SR-BI in the regulation of HDL metabolism in gene knockout mouse models.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD36,
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoprotein A-I,
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E,
http://linkedlifedata.com/resource/pubmed/chemical/Lipase,
http://linkedlifedata.com/resource/pubmed/chemical/Lipc protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, HDL,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylcholine-Sterol...,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipid Transfer Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Scavenger,
http://linkedlifedata.com/resource/pubmed/chemical/apolipoprotein E-rich HDL
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
149-54
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15539616-Animals,
pubmed-meshheading:15539616-Antigens, CD36,
pubmed-meshheading:15539616-Apolipoprotein A-I,
pubmed-meshheading:15539616-Apolipoproteins E,
pubmed-meshheading:15539616-Breeding,
pubmed-meshheading:15539616-Endothelium,
pubmed-meshheading:15539616-Lipase,
pubmed-meshheading:15539616-Lipids,
pubmed-meshheading:15539616-Lipoproteins,
pubmed-meshheading:15539616-Lipoproteins, HDL,
pubmed-meshheading:15539616-Membrane Proteins,
pubmed-meshheading:15539616-Mice,
pubmed-meshheading:15539616-Mice, Inbred C57BL,
pubmed-meshheading:15539616-Mice, Inbred Strains,
pubmed-meshheading:15539616-Mice, Knockout,
pubmed-meshheading:15539616-Nuclear Magnetic Resonance, Biomolecular,
pubmed-meshheading:15539616-Phosphatidylcholine-Sterol O-Acyltransferase,
pubmed-meshheading:15539616-Phospholipid Transfer Proteins,
pubmed-meshheading:15539616-Receptors, Immunologic,
pubmed-meshheading:15539616-Receptors, Scavenger
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pubmed:year |
2005
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pubmed:articleTitle |
Differential additive effects of endothelial lipase and scavenger receptor-class B type I on high-density lipoprotein metabolism in knockout mouse models.
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pubmed:affiliation |
Section of Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, and St. Luke's Episcopal Hospital, Houston, Tex 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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