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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1992-4-28
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pubmed:abstractText |
Analysis of epidermal growth factor (125J-EGF) binding to human red cells revealed the presence of two classes of binding sites with apparent equilibrium dissociation constants (app.Kd) in the 10(-10)-10(-9) M and in the 10(-8) M range, respectively. The number of binding sites/cell ranged between 600 and 2,400 for the high-affinity binding site and between 7,200 and 23,000 for the low-affinity site. No differences were seen in the apparent Kd values for both types of binding sites between red cells obtained from donors with different ABO-blood groups. An increase in the number of high affinity EGF binding sites was observed in donors with blood group A1-erythrocytes as compared to red cells taken from donors with blood groups O and B.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0361-8609
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
239-41
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:1553951-ABO Blood-Group System,
pubmed-meshheading:1553951-Binding Sites,
pubmed-meshheading:1553951-Blood Donors,
pubmed-meshheading:1553951-Epidermal Growth Factor,
pubmed-meshheading:1553951-Erythrocytes,
pubmed-meshheading:1553951-Genetic Variation,
pubmed-meshheading:1553951-Histocompatibility,
pubmed-meshheading:1553951-Humans,
pubmed-meshheading:1553951-Isoantigens,
pubmed-meshheading:1553951-Protein Binding,
pubmed-meshheading:1553951-Receptor, Epidermal Growth Factor,
pubmed-meshheading:1553951-Regression Analysis
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pubmed:year |
1992
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pubmed:articleTitle |
Epidermal growth factor binding sites on human erythrocytes in donors with different ABO blood groups.
|
pubmed:affiliation |
Physiologisches Institut, Universität München, West Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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