Source:http://linkedlifedata.com/resource/pubmed/id/15539333
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
9
|
| pubmed:dateCreated |
2004-11-12
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| pubmed:abstractText |
We have previously shown that beta-carotene supplementation of the diets of healthy U.S. mothers increases serum and milk beta-carotene concentrations. Building on these results, we investigated the possibility that beta-carotene supplementation could enhance the vitamin A status of mothers and their nursing infants. Three 30-mg doses of beta-carotene were administered on 3 consecutive days to 44 lactating mothers who had vitamin-A-poor diets. Concentrations of maternal serum and milk carotenoids and retinol were evaluated at baseline and after 2 and 3 days of supplementation. Infant serum carotenoids and retinol were measured at baseline and 2 days following maternal supplementation. beta-Carotene supplementation markedly elevated maternal serum and milk beta-carotene concentrations (nine- and sevenfold, respectively) and resulted in smaller, transient increases of alpha-carotene, lycopene, and beta-cryptoxanthin concentrations in maternal serum. Maternal serum and milk retinol were unchanged in response to the treatment. In contrast, maternal beta-carotene supplementation significantly increased infant serum retinol (P </= 0.001) and beta-carotene concentrations remained unchanged. These results imply that breast milk beta-carotene can supply retinol for the nursing infant. Further research is needed to identify the site of bioconversion of milk-derived beta-carotene to retinol and to describe the factors that regulate this process.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:status |
PubMed-not-MEDLINE
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| pubmed:month |
Sep
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| pubmed:issn |
0955-2863
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
10
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
532-8
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| pubmed:year |
1999
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| pubmed:articleTitle |
Short-term beta-carotene supplementation of lactating mothers consuming diets low in vitamin A.
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| pubmed:affiliation |
The University Department of Biochemistry, University of Arizona, Tucson, AZ 85721, USA.
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| pubmed:publicationType |
Journal Article
|