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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2004-12-13
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pubmed:abstractText |
Exogenous reactive oxygen species (ROS) induces DNA damage. Manganese superoxide dismutase (SOD2) catalyzes the dismutation of superoxide radicals, a major type of ROS, into hydrogen peroxide. p53 is a tumor suppressor gene, and X-ray cross-complementing group 1 (XRCC1) is involved in the base-excision repair of ROS-induced DNA damage.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
101
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2802-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15534883-Adult,
pubmed-meshheading:15534883-Aged,
pubmed-meshheading:15534883-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:15534883-Case-Control Studies,
pubmed-meshheading:15534883-DNA-Binding Proteins,
pubmed-meshheading:15534883-Female,
pubmed-meshheading:15534883-Gene Frequency,
pubmed-meshheading:15534883-Genes, p53,
pubmed-meshheading:15534883-Genetic Predisposition to Disease,
pubmed-meshheading:15534883-Genotype,
pubmed-meshheading:15534883-Humans,
pubmed-meshheading:15534883-Lung Neoplasms,
pubmed-meshheading:15534883-Male,
pubmed-meshheading:15534883-Middle Aged,
pubmed-meshheading:15534883-Odds Ratio,
pubmed-meshheading:15534883-Polymorphism, Genetic,
pubmed-meshheading:15534883-Smoking,
pubmed-meshheading:15534883-Superoxide Dismutase
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pubmed:year |
2004
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pubmed:articleTitle |
The SOD2 Val/Val genotype enhances the risk of nonsmall cell lung carcinoma by p53 and XRCC1 polymorphisms.
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pubmed:affiliation |
Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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