Source:http://linkedlifedata.com/resource/pubmed/id/15534263
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
2004-11-9
|
pubmed:abstractText |
The authors examined the association of the alcohol dehydrogenase 2 (ADH2) genotype with vascular events in community-dwelling Japanese (1,102 men/1,093 women). The allele ADH2*2 encodes an isozyme with a higher level of activity than ADH2*1. Here, the authors show that the ADH2*1 carriage is associated with high prevalence of cerebral infarction and lacunae in men. Multiple regression analyses confirmed that the risk of lacunae and cerebral infarction was increased by the ADH2*1 allele.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
1526-632X
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:day |
9
|
pubmed:volume |
63
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1711-3
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:15534263-Adult,
pubmed-meshheading:15534263-Aged,
pubmed-meshheading:15534263-Alcohol Dehydrogenase,
pubmed-meshheading:15534263-Alleles,
pubmed-meshheading:15534263-Asian Continental Ancestry Group,
pubmed-meshheading:15534263-Cerebral Infarction,
pubmed-meshheading:15534263-Female,
pubmed-meshheading:15534263-Genetic Predisposition to Disease,
pubmed-meshheading:15534263-Genetic Variation,
pubmed-meshheading:15534263-Humans,
pubmed-meshheading:15534263-Japan,
pubmed-meshheading:15534263-Magnetic Resonance Imaging,
pubmed-meshheading:15534263-Male,
pubmed-meshheading:15534263-Middle Aged
|
pubmed:year |
2004
|
pubmed:articleTitle |
Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae.
|
pubmed:affiliation |
Department of Biochemistry and Cell Biology, Institute of Development and Aging Sciences, Graduate School of Medicine, Nippon Medical School, Kawasaki, Kanagawa, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|