pubmed-article:15534114 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:15534114 | lifeskim:mentions | umls-concept:C0039286 | lld:lifeskim |
pubmed-article:15534114 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:15534114 | lifeskim:mentions | umls-concept:C0851344 | lld:lifeskim |
pubmed-article:15534114 | lifeskim:mentions | umls-concept:C0232970 | lld:lifeskim |
pubmed-article:15534114 | lifeskim:mentions | umls-concept:C1511291 | lld:lifeskim |
pubmed-article:15534114 | pubmed:issue | 21 | lld:pubmed |
pubmed-article:15534114 | pubmed:dateCreated | 2004-11-9 | lld:pubmed |
pubmed-article:15534114 | pubmed:abstractText | To optimize treatment strategies for postmenopausal breast cancer patients, we investigated the efficacy of the steroidal aromatase inhibitor exemestane alone or in combination with the antiestrogen tamoxifen in a xenograft model of postmenopausal breast cancer. We also determined the effects of these agents in sequential second-line therapy and the effect of the nonsteroidal aromatase inhibitor letrozole on tumors that progressed on the above treatments. Experimental: Aromatase-transfected human estrogen receptor-positive breast cancer cells (MCF-7Ca) were grown as tumors in ovariectomized athymic mice. Animals received subcutaneous injection with vehicle, tamoxifen, exemestane, tamoxifen plus exemestane, and letrozole. Tumor volumes were measured weekly. | lld:pubmed |
pubmed-article:15534114 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15534114 | pubmed:language | eng | lld:pubmed |
pubmed-article:15534114 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15534114 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:15534114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15534114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15534114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15534114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15534114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15534114 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15534114 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:15534114 | pubmed:month | Nov | lld:pubmed |
pubmed-article:15534114 | pubmed:issn | 1078-0432 | lld:pubmed |
pubmed-article:15534114 | pubmed:author | pubmed-author:IngleJames... | lld:pubmed |
pubmed-article:15534114 | pubmed:author | pubmed-author:LongBrian JBJ | lld:pubmed |
pubmed-article:15534114 | pubmed:author | pubmed-author:JelovacDanije... | lld:pubmed |
pubmed-article:15534114 | pubmed:author | pubmed-author:GoloubevaOlga... | lld:pubmed |
pubmed-article:15534114 | pubmed:author | pubmed-author:BrodieAngela... | lld:pubmed |
pubmed-article:15534114 | pubmed:author | pubmed-author:HandrattaVenk... | lld:pubmed |
pubmed-article:15534114 | pubmed:author | pubmed-author:MacedoLuciana... | lld:pubmed |
pubmed-article:15534114 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:15534114 | pubmed:day | 1 | lld:pubmed |
pubmed-article:15534114 | pubmed:volume | 10 | lld:pubmed |
pubmed-article:15534114 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:15534114 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:15534114 | pubmed:pagination | 7375-81 | lld:pubmed |
pubmed-article:15534114 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:15534114 | pubmed:meshHeading | pubmed-meshheading:15534114... | lld:pubmed |
pubmed-article:15534114 | pubmed:year | 2004 | lld:pubmed |
pubmed-article:15534114 | pubmed:articleTitle | Effects of exemestane and tamoxifen in a postmenopausal breast cancer model. | lld:pubmed |
pubmed-article:15534114 | pubmed:affiliation | Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA. | lld:pubmed |
pubmed-article:15534114 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:15534114 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:15534114 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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