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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
21
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pubmed:dateCreated |
2004-11-9
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pubmed:abstractText |
The RNASEL gene has been proposed as a candidate gene for the HPC1 locus through a positional cloning and candidate gene approach. Cosegregation between the truncating mutation E265X and disease in a hereditary prostate cancer (HPC) family and association between prostate cancer risk and the common missense variant R462Q has been reported. To additionally evaluate the possible role of RNASEL in susceptibility to prostate cancer risk, we performed a comprehensive genetic analysis of sequence variants in RNASEL in the Swedish population.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
7150-6
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pubmed:dateRevised |
2011-6-17
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pubmed:meshHeading |
pubmed-meshheading:15534086-Adult,
pubmed-meshheading:15534086-Aged,
pubmed-meshheading:15534086-DNA,
pubmed-meshheading:15534086-Endoribonucleases,
pubmed-meshheading:15534086-Family Health,
pubmed-meshheading:15534086-Genetic Linkage,
pubmed-meshheading:15534086-Genotype,
pubmed-meshheading:15534086-Haplotypes,
pubmed-meshheading:15534086-Heterozygote,
pubmed-meshheading:15534086-Humans,
pubmed-meshheading:15534086-Male,
pubmed-meshheading:15534086-Middle Aged,
pubmed-meshheading:15534086-Mutation,
pubmed-meshheading:15534086-Mutation, Missense,
pubmed-meshheading:15534086-Odds Ratio,
pubmed-meshheading:15534086-Polymorphism, Single Nucleotide,
pubmed-meshheading:15534086-Prostatic Neoplasms,
pubmed-meshheading:15534086-Sequence Analysis, DNA
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pubmed:year |
2004
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pubmed:articleTitle |
Genetic analysis of the RNASEL gene in hereditary, familial, and sporadic prostate cancer.
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pubmed:affiliation |
Department of Radiation Sciences, Oncology, and Medical Biosciences, Pathology, University of Umeå, Umeå, Sweden. fredrik.wiklund@oc.umu.se
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pubmed:publicationType |
Journal Article
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