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rdf:type |
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lifeskim:mentions |
umls-concept:C0003018,
umls-concept:C0017262,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0079904,
umls-concept:C0185117,
umls-concept:C0282554,
umls-concept:C0301630,
umls-concept:C0441655,
umls-concept:C0441994,
umls-concept:C0597360,
umls-concept:C1412113,
umls-concept:C1958507,
umls-concept:C2911684
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pubmed:issue |
2
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pubmed:dateCreated |
2004-11-8
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pubmed:abstractText |
Angiotensin converting enzyme (ACE) inhibitors significantly improve survival in patients with atherosclerosis. Although ACE inhibitors reduce local angiotensin II (AngII) formation, serine proteases form AngII to an enormous amount independently from ACE. Therefore, our study concentrates on the effect of the ACE-inhibitor ramiprilat on chemokine release, AngII receptor (ATR) expression, and NF-kappaB activity in monocytes stimulated with AngII.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II Type 1 Receptor...,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II Type 2 Receptor...,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin-Converting Enzyme...,
http://linkedlifedata.com/resource/pubmed/chemical/CCL2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines,
http://linkedlifedata.com/resource/pubmed/chemical/Imidazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-8,
http://linkedlifedata.com/resource/pubmed/chemical/Losartan,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/PD 123319,
http://linkedlifedata.com/resource/pubmed/chemical/Peptidyl-Dipeptidase A,
http://linkedlifedata.com/resource/pubmed/chemical/Pyridines,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Ramipril,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 1,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Angiotensin, Type 2,
http://linkedlifedata.com/resource/pubmed/chemical/Simvastatin,
http://linkedlifedata.com/resource/pubmed/chemical/ramiprilat
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
325
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
532-40
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:15530425-Angiotensin II,
pubmed-meshheading:15530425-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:15530425-Angiotensin II Type 2 Receptor Blockers,
pubmed-meshheading:15530425-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:15530425-Cell Line,
pubmed-meshheading:15530425-Chemokine CCL2,
pubmed-meshheading:15530425-Chemokines,
pubmed-meshheading:15530425-Down-Regulation,
pubmed-meshheading:15530425-Drug Interactions,
pubmed-meshheading:15530425-Endothelium, Vascular,
pubmed-meshheading:15530425-Humans,
pubmed-meshheading:15530425-Imidazoles,
pubmed-meshheading:15530425-Interleukin-8,
pubmed-meshheading:15530425-Losartan,
pubmed-meshheading:15530425-Monocytes,
pubmed-meshheading:15530425-NF-kappa B,
pubmed-meshheading:15530425-Peptidyl-Dipeptidase A,
pubmed-meshheading:15530425-Pyridines,
pubmed-meshheading:15530425-RNA, Messenger,
pubmed-meshheading:15530425-Ramipril,
pubmed-meshheading:15530425-Receptor, Angiotensin, Type 1,
pubmed-meshheading:15530425-Receptor, Angiotensin, Type 2,
pubmed-meshheading:15530425-Simvastatin,
pubmed-meshheading:15530425-Umbilical Veins
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pubmed:year |
2004
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pubmed:articleTitle |
ACE inhibition lowers angiotensin II-induced chemokine expression by reduction of NF-kappaB activity and AT1 receptor expression.
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pubmed:affiliation |
Medical Clinic II, University of Technology, Dresden, Germany. AlexanderSchmeis@t-online.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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